Home > Books > Essentials of Pharmaceutical Preformulation
Essentials of Pharmaceutical Preformulation
View PDF

Essentials of Pharmaceutical Preformulation

Publication Year: 2012
Edition: 1st
Authors/Editor: Gaisford, Simon; Saunders, Mark
Publisher: Wiley
ISBN: 978-0-470-97635-7
  • Description
  • Details
  • Collections

A study guide which describes the basic principles of pharmaceutical physicochemical characterization.

Successful preformulation requires knowledge of fundamental molecular concepts (solubility, ionisation, partitioning, hygroscopicity and stability) and macroscopic properties (physical form, such as the crystalline and amorphous states, hydrates, solvates and co-crystals and powder properties), familiarity with the techniques used to measure them and appreciation of their effect on product performance, recognising that often there is a position of compromise to be reached between product stability and bioavailability.

This text introduces the basic concepts and discusses their wider implication for pharmaceutical development, with reference to many case examples of current drugs and drug products. Special attention is given to the principles and best-practice of the analytical techniques that underpin preformulation (UV spectrophotometry, TLC, DSC, XRPD and HPLC). The material is presented in the typical order that would be followed when developing a medicine and maps onto the indicative pharmacy syllabus of the Royal Pharmaceutical Society of Great Britain

  • Platform:
    Ovid
  • Publisher: Wiley
  • Product Type: Book
  • Author/Editor: Gaisford, Simon; Saunders, Mark
  • ISBN: 978-0-470-97635-7
  • Specialty:
    Pharmaceutical Science
    Pharmacology
  • Language: English
  • Edition: 1st
  • Pages: 268
  • Illustrations: 0
  • Year: 2012

Essentials of Pharmaceutical Preformulation is included in the following Collections:

Free Instant Access
This Month

JOTM
FSTA® Food Science and Technology Abstracts FSTA® covers topics relating to every aspect of the food chain including all the major food commodities plus biotechnology, microbiology, food safety, and nutrition.
JOTM
Northern Light Life Sciences Conference Abstracts This grey literature database provides unique access to 2.5 million abstracts and posters from medical and life sciences conferences from across the globe.
JOTM
JBJS Case Connector This cross-referenced online journal compiles symptoms, conditions, and demographic details to empower surgeons to find cases similar to theirs and to mine the database to reveal emerging trends and identify patterns.
JOTM
Diseases of the Colon & Rectum Recognized as the authority in conditions affecting the colon, rectum, and anus this journal includes peer-reviewed original research, reviews, selected abstracts of the literature, and more.

Noteworthy

Doody's Featured Books
Avoiding Common Errors in the Emergency Department
Covers 400 errors commonly made by residents, medical students, attendings, nurse practitioners, and physician assistants in the emergency department, and gives practical, easy-to-remember tips for avoiding these pitfalls.

A Practical Guide to Dermoscopy
Helps you use Dr. Orit Markowitz's unique, color wheel approach to solve difficult diagnostic challenges, particularly when it comes to distinguishing between malignant and benign conditions, expediting effective treatment.